Title:
Head of Medical Evidence Generation and Technical Evolution UK & Ireland

Company:
Ipsen Ltd

Job Description:

Head of Medical Evidence Generation and Technical Evolution UK & Ireland

Location: London Paddington (3 days a week in office, 2 from home)

As the Head of Medical Evidence Generation & Technical Evolution, you will play a crucial role in overseeing clinical research activities, driving the generation of robust evidence, including real-world evidence (RWE), and ensuring that Ipsen remains at the forefront of medical and digital innovation, such as generative AI applications in medical affairs.

This position bridges scientific excellence, regulatory alignment, and innovative strategy to enhance our value proposition and support our business goals. Given Ipsen's outsourced research delivery model for clinical trials, observational studies, and RWE generation, you will work closely with global R&D, Global Medical Affairs, and Vendors/CROs to ensure robust UK input into study design, feasibility, site selection, and delivery.

Key Responsibilities

Oversight of Clinical Research

• Lead the planning, design, and execution of UK clinical research as appropriate to support regulatory submissions, market access, and lifecycle management.
• Be responsible for ensuring the effective delivery of Ipsen's sponsored research programme in the UK, including oversight of the clinical research dashboard and mentoring, teaching and direction of the MSLs to ensure delivery of studies on time and to budget.
• Ensure alignment between clinical objectives and organizational goals while maintaining compliance with GXP and global regulatory standards.
• Collaborate with Clinical Development, Medical Affairs, and investigators to deliver our internally and externally sponsored study portfolio on time and to budget.
• Manage budgets and timelines for assigned projects to optimize delivery and output.

Evidence Generation

• Partner with the Product Medical Directors and their teams to develop and deliver evidence generation strategies (clinical and RWE) to demonstrate the safety, efficacy, and value of products.
• Provide scientific leadership for observational studies, patient registries, pragmatic trials, and digital health-related evidence initiatives.
• Partner with Market Access, Health Economics, and Outcomes Research (HEOR) teams to ensure evidence strategies align with payer and policymaker requirements.
• Review emerging data to shape strategic plans and refine clinical narratives.

Technical Leadership in Medical Affairs

Lead the organization's evolution in adopting next-generation technologies in Medical Affairs, such as:

• Generative AI for evidence synthesis, predictive modelling, and HCP/patient engagement.
• Advanced analytics for RWE and trial optimization.
• Digital platforms for decentralized clinical trials and digital biomarkers.
• Collaborate with IT and external vendors to identify, test, and deploy innovative tools for enhanced scientific capabilities.

Cross-Functional Collaboration

• Act as a key point of contact between Medical Affairs, Clinical Development, and Commercial functions.
• Represent Medical Affairs in cross-functional discussions to ensure evidence initiatives are scientifically and strategically aligned with overall objectives.
• Establish collaborations with academic institutions, healthcare systems, and industry partners for broader scientific engagements.

Compliance and Knowledge Dissemination

• Ensure compliance with all ethical, legal, and regulatory requirements related to clinical trials, evidence generation, and medical technologies.
• Lead the dissemination of clinical trial data and RWE insights through peer-reviewed publications, conferences, and internal updates.
• Stay abreast of evolving regulations and industry trends.

Requirements:

• Bachelor's life science degree or Master's degree or equivalent / PhD or MBChB
• Proven track record in Medical Affairs, Clinical Research, or Evidence Generation roles within the pharmaceutical industry.
• Strong clinical trials experience in the pharmaceutical industry or within CROs.
• Experience with the implementation of cutting-edge medical technologies.
• Strong understanding of clinical trial planning (site) management and metrics
• Familiarity with regulatory requirements and compliance in global clinical research.
• Deep understanding of clinical trial processes, including Phase I-IV trials and RWE methodologies.
• Expertise in data analytics, advanced digital tools, and generative AI.
• Strategic and analytical thinking with the ability to integrate complex scientific and technical information into actionable plans.
• Strong interpersonal, collaborative, and cross-functional leadership skills.
• Commitment to ethical conduct and maintaining high scientific standards
• Languages: Excellent oral and written English

IPSEN is committed to equality of opportunity for all staff and applications, individuals are encouraged to apply regardless of age, disability, sex, gender reassignment, sexual orientation, pregnancy and maternity, race, religion or belief and marriage and civil partnerships.