SENIOR DIRECTOR, EVIDENCE GENERATION AND PUBLICATIONS

At Day One, we are focused on advancing first- or best-in-class medicines for childhood and adult diseases with equal intensity. We were founded to address the lack of new therapies resulting from the traditional drug development model, that has left children with cancer and their families waiting too long for new, life-changing treatments. Our aim is to accelerate better, targeted treatments so patients of any age can look forward from 'day one' to the future they've envisioned.

POSITION SUMMARY:

The Senior Director, Evidence Generation and Publications will play a critical leadership role within the Medical Affairs organization. This individual will be responsible for leading the cross-functional development and execution of integrated evidence generation and scientific publication strategies across the Day One portfolio, focusing on addressing key evidence gaps and ensuring timely and impactful data dissemination.

This role includes oversight of all Medical Affairs driven evidence generation across a variety of data sources, including post-hoc analyses from sponsored trials, real-world evidence (RWE), health economics and outcomes research (HEOR), and externally sponsored research activities such as ISTs. The Senior Director will also ensure that all publication activities align with the scientific communication platform and support Day One's mission to deliver transformative therapies to pediatric and underserved cancer populations. This position reports to the Vice President of Medical Affairs and has the potential to be fully remote. Travel of 20%-30% will be required for scientific conferences and in-person meetings.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

• Lead the cross-functional development of the Integrated Evidence Generation Plan (IEGP) to identify and prioritize evidence gaps across the Day One portfolio and develop corresponding plans to address them.
• Design and lead initiatives for evidence generation, including post hoc analyses, RWE, and HEOR studies, while ensuring strategic alignment and fostering cross-functional collaboration.
• Oversee the strategy and operational execution of Investigator-Sponsored Trials (ISTs) and serve as chair of the External Research Committee (ERC) to ensure alignment with the company's scientific objectives.
• Oversee the development and maintenance of the Strategic Publication Plan, coordinating cross-functional contributions and ensuring the visibility of key messages, timelines, and data disclosures.
• Ensure that all publications and presentations are consistent with the Scientific Communication Platform and uphold high standards of scientific integrity and compliance.
• Collaborate with internal stakeholders (Clinical Development, Commercial, Regulatory, Market Access) to ensure the coordination and alignment of evidence and publication initiatives.
• Serve as the internal subject matter expert for evidence generation and publications, while offering strategic leadership across functions.
• Ensure clear and ongoing internal communication regarding all evidence generation and publication activities, timelines, and milestones.
• Mentor and manage team members while contributing to the development of a high-performing, collaborative Medical Affairs function.
• Ensure compliance with applicable regulatory, legal, and ethical standards in all external research and publication activities.

QUALIFICATIONS

• An advanced degree (PharmD, PhD, MD) in a relevant scientific or medical discipline is required.
• A minimum of 12 years of experience in Medical Affairs or a related industry, including at least 5 years in oncology and 5 years in a leadership role.
• Proven experience in integrated evidence generation, including real-world evidence (RWE) and health economics and outcomes research (HEOR), with demonstrated success in leading cross-functional teams.
• Proven expertise in scientific publications and congress strategy, including authorship planning and peer-reviewed publications.
• Thorough understanding of external research governance, GPP/ICMJE publication standards, and compliance requirements for industry-sponsored communications.
• Demonstrated ability to build and maintain relationships with key internal and external stakeholders, including opinion leaders and academic collaborators.
• Excellent written and verbal communication skills, along with a strong ability to influence across functions and levels.
• A high degree of scientific and operational rigor, attention to detail, and a commitment to excellence.

The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification.

INTERVIEW INTEGRITY

At Day One, we expect each candidate to engage authentically, representing their true qualifications and experiences. As part of our screening process, we will conduct several interviews and background verification. This ensures candidates have the skills they claim and align with our values. We are excited to learn more about you and to create a genuine experience for everyone.

COMPENSATION AND BENEFITS

The salary range for this position is $300,000 - $315,000. Day One considers a range of factors when determining base compensation. These considerations mean actual compensation will vary.

Please visit https://www.dayonebio.com/benefits to see our competitive benefits.

DISCLAIMER

Day One Biopharmaceuticals is committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law.

Employment is conditioned upon full vaccination from the COVID-19 virus, including submission of documented proof thereof, as of the start date. Day One Biopharmaceuticals will comply with applicable law regarding the reasonable accommodation of individuals who are not vaccinated because of a disability and/or a sincerely held religious belief.

We are unable to sponsor or take over sponsorship of any applicant work visas at this time.

Recruitment & Staffing Agencies: Day One Biopharmaceuticals does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Day One Biopharmaceuticals or its employees is strictly prohibited unless contacted directly by Day One Biopharmaceutical's internal HR team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Day One Biopharmaceuticals, and Day One Biopharmaceuticals will not owe any referral or other fees with respect thereto.